Reproductive ageing and ovarian function: is the early follicular phase FSH rise necessary to maintain adequate secretory function in older ovulatory women?

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Reproductive ageing and ovarian function: is the early follicular phase FSH rise necessary to maintain adequate secretory function in older ovulatory women?

BACKGROUND Serum FSH elevations and decreases in inhibin B have been consistently demonstrated in the early follicular phase of cycles in women of advanced reproductive age. However, secretory products of the dominant follicle (estradiol and inhibin A) in the serum of older ovulatory women are maintained at levels similar to those of their younger counterparts. The goal of this investigation wa...

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Women with consistently or variably elevated early follicular phase FSH.

Sir, We thank Drs El Hakim and Cahil for their interest and reaction to our paper (de Koning et al. 2008). It is true that the highest measured FSH level is the one that makes clinicians aware of the possible low ovarian reserve. It is known that a normal or moderately elevated FSH can still be found in women with low ovarian reserve due to variable FSH levels and possibly variable cohort size....

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The Effect of Ligation of the Ovarian Artery on Ovarian Follicular Function in Rats

In the present study was performed to evaluate the follicular growth and hormonal changes after ovarian artery ligation in rats. Fifty six virgin 90-day–old female rats were used. The rats were chosen from 100 female rats by a vaginal smear, which showed that they were synchronized in estrous phase of the menstrual cycle. Animals were kept in seven cages (n=8 in each) at a temperature of 22 ± 2...

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Timing of FSH administration for ovarian stimulation in normo-ovulatory women: comparison of an early or a mid follicular phase initiation of a short-term treatment.

BACKGROUND In normo-ovulatory infertile women undergoing mild ovarian stimulation out of IVF, FSH stimulation regimen must be carefully adjusted to control the number of recruited follicles and to prevent multiple pregnancies. The aim of this prospective study was to assess the effect of the timing of FSH administration (fixed dose and duration) on the number of large follicles. METHODS Women...

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Lack of correlation between maximum early follicular phase serum follicle stimulating hormone concentrations and menstrual cycle characteristics in women under the age of 35 years.

The gradual increase in follicle stimulating hormone (FSH) concentrations in women approaching menopause results from the depletion of the ovarian follicular pool, a process referred to as 'ovarian ageing'. This study investigates whether variable endogenous FSH concentrations, as have been observed in normo-ovulatory young women, are related to menstrual cycle characteristics, including predic...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2005

ISSN: 1460-2350,0268-1161

DOI: 10.1093/humrep/deh544